BOUTIQUE精品展示
參與三磷酸核苷水解的酶是生化研究的重點(diǎn),旨在了解和治療癌癥、病毒感染、心血管和運(yùn)動(dòng)障礙等相關(guān)疾病的細(xì)胞過程。為了闡明這些酶的作用機(jī)制,需要在其三磷酸結(jié)合狀態(tài)中將酶捕獲,而天然核苷酸的水解速率通常會(huì)阻礙此過程,因此需要使用核苷酸類似物,其水解速率要小得多,甚至完全耐水解。
Jena Bioscience由德國馬普所(MPI)的知名分子生物學(xué)家于1998年共同創(chuàng)辦,致力于為全球的科研院所,醫(yī)院,制藥企業(yè)和診斷試劑盒生產(chǎn)企業(yè)提供各類試劑與原料, 其中含有豐富的不可水解的核苷酸類似物:
α-磷酸修飾的核苷酸
類別 |
品名 |
貨號(hào) |
Adenosine Nucleotides |
AMPαS - Solution |
NU-1161 |
AMPαS – Solid |
NU-1161 |
|
ATPαS |
NU-408 |
|
dADPαS |
NU-1165 |
|
dATPαS |
NU-426 |
|
dAMPαS |
NU-430 |
|
Guanosine Nucleotides |
GMPαS |
NU-1160 |
GTPαS |
NU-409 |
|
dGDPαS |
NU-1164 |
|
dGTPαS |
NU-424 |
|
Uridine Nucleotides |
UTPαS |
NU-411 |
Cytidine Nucleotides |
CTPαS |
NU-436 |
dCMPαS |
NU-447 |
|
dCTPαS |
NU-425 |
|
Thymidine Nucleotides |
dTTPαS |
NU-410 |
α,β不可水解核苷酸
類別 |
品名 |
貨號(hào) |
Adenosine Nucleotides |
ApCp |
NU-420 |
ApCpp |
NU-421 |
|
dApCpp |
NU-432 |
|
ApNHp |
NU-448 |
|
ApNHpp |
NU-449 |
|
dApNHpp |
NU-443 |
|
Guanosine Nucleotides |
GpCp |
NU-414 |
GpCpp |
NU-405S |
|
dGpCpp |
NU-431 |
|
dGpNHpp |
NU-440 |
|
NPE-caged-GpCpp |
NU-306 |
|
6-Thio-GpCp |
NU-417 |
|
Cytidine Nucleotides |
CpCp |
NU-441 |
CpCpp |
NU-438 |
|
dCpCpp |
NU-437 |
|
CpNHpp |
NU-264 |
|
dCpNHpp |
NU-439 |
|
Thymidine Nucleotides |
dTpCpp |
NU-895 |
dTpNHpp |
NU-907 |
β-磷酸修飾的核苷酸
類別 |
品名 |
貨號(hào) |
Adenosine Nucleotides
|
ADPβS |
NU-433 |
AppNH2 |
NU-1126 |
|
Guanosine Nucleotides |
GDPβS |
NU-427 |
GppNH2 |
NU-1136 |
|
Uridine Nucleotides |
UDPβS |
NU-442 |
β,γ不可水解核苷酸
類別 |
品名 |
貨號(hào) |
Adenosine Nucleotides
|
AppCp |
NU-422 |
dAppCp |
NU-259 |
|
AppNHp |
NU-407 |
|
dAppNHp |
NU-257 |
|
Mant-AppNHp |
NU-214 |
|
NPE-caged-AppNHp |
NU-305 |
|
EDA-AppNHp |
NU-810 |
|
Etheno-AppNHp |
NU-1104 |
|
8-Bromo-AppNHp |
NU-116 |
|
8-Iodo-AppNHp |
NU-115 |
|
2'-Bromo-dAppNHp |
NU-104 |
|
2'-Iodo-dAppNHp |
NU-103 |
|
Guanosine Nucleotides |
GppCp |
NU-402 |
dGppCp |
NU-260 |
|
GppNHp |
NU-401 |
|
GppNHp |
NU-899 |
|
dGppNHp |
NU-258 |
|
Mant-GppCp |
NU-881 |
|
Mant-GppNHp |
NU-207 |
|
Mant-dGppNHp |
NU-208 |
|
6-Thio-GppCp |
NU-418 |
|
6-Thio-GppNHp |
NU-419 |
|
TNP-GppNHp |
NU-218 |
|
Xanthosine Nucleotides |
XppCp |
NU-423 |
XppNHp |
NU-996 |
|
Mant-XppNHp |
NU-211 |
|
NPE-caged-XppNHp |
NU-308 |
|
Inosine Nucleotides |
IppNHp |
NU-1204 |
Uridine Nucleotides |
UppNHp – Solid |
NU-415 |
UppCp |
NU-255 |
|
dUppCp |
NU-263 |
|
Cytosine Nucleotides |
CppCp |
NU-254 |
dCppCp |
NU-261 |
|
Thymidine Nucleotides |
dTppCp |
NU-262 |
γ-磷酸修飾的核苷酸
類別 |
品名 |
貨號(hào) |
Adenosine Nucleotides |
ATPγS |
NU-406 |
dATPγS |
NU-265 |
|
Mant-ATPγS |
NU-232 |
|
2-Iodo-ATPγS |
NU-905 |
|
N6-Benzyl-ATPγS |
NU-241 |
|
Guanosine Nucleotides |
GTPγS |
NU-412 |
dGTPγS |
NU-266 |
|
Mant-GTPγS |
NU-209 |
|
Xanthosine Nucleotides |
XTPγS |
NU-404 |
Inosine Nucleotides |
ITPγS |
NU-413 |
Mant-ITPγS |
NU-981 |
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